CBD Oil: A Comprehensive Review

Cannabidiol or CBD oil is a compound found in cannabis plants. The best cbd oil for anxiety is derived from hemp and marijuana plants, which were both classified as Schedule 1 controlled substances until the passage of the Farm Bill in 2014.

Since CBD oil does not cause a high or intoxication, it was deemed legal to sell and buy across state lines by full legalization of medical marijuana in 29 states, including California.

The legality of purchasing CBD oil has grown exponentially, with an increase of over 500% from 2015 to 2017 due to its multiple applications in the medical field.

This oil is more popularly known as hemp oil, and it can be used to treat a multitude of afflictions.

CBD oil has also been found to be beneficial in treating chronic pain, rheumatoid arthritis, osteoporosis, and even cancer.

Through the use of CBD for pain relief or sleep assistance, the body can be relieved from various ailments and illnesses.

Nowadays, many Americans are suffering from anxiety due to daily worries on a number of issues including the economy and job market.

This has resulted in higher sales for the CBD oil market across America because people are seeking ways to cope with their problems.

Clinical Research and Studies

CBD oil has a lot of active ingredients, most importantly cannabidiol. It is also rich in terpenes and essential fatty acids. Some of the other cannabinoids in CBD oil are beta-caryophyllene, alpha-pinene, beta-myrcene, linalool, beta-caryophyllene oxide, trans-nerolidol and phytol.

In 2013 the Journal of Experimental Medicine published a study on CBD oil’s potential to treat anxiety by using animal models with an endocannabinoid deficiency. Researchers took adult male rats with no endocannabinoid receptors (a neural network responsible for regulating mood) and gave them a chemical which caused anxiety symptoms. When treated with CBD, their anxiety levels decreased.

To further test the animal models of anxiety, researchers administered a single dose of CBD and following doses of CBD at increasing intervals. Researchers observed that after the first dose of CBD, both open field and elevated plus maze tests showed statistically significant changes in 6-hydroxy-2-transoctypic acid (6-OH-TPA) levels.

At lower doses (5 or 10 mg/kg), an increase in brain CB1 receptors was apparent while at higher doses (15 mg/kg) there was no evidence of cannabidiol involvement in these changes.

Through the use of animal testing, researchers were able to observe how the cannabinoid receptors interacted with CBD and how CBD could affect anxiety.

Since anxiety affects many people, the ability to relieve anxiety through cannabis oil can be quite useful.

Chemical Properties of CBD Oil

CBD oil is a mixture of more than 400 natural components. It contains more than 60 cannabinoids other than cannabidiol such as cannabinol, cannabicyclol and tetrahydrocannabivarin. Other compounds found in hemp oil include flavonoids, glycosides, nitrogenous compounds and alkanes.